物质信息
ID:373942
(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Hydrobromide
名称和标识
IUPAC标准名
2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid hydrobromide
IUPAC传统名
AMPA hydrobromide
别名
γ-Amino-3-hydroxy-5-methylisoxazole-4-propionic Αcid Hydrobromide(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideAMPAD,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Hydrobromide
数据登录号
CAS号
化合物性质
理化性质
溶解度
Methanol
Water
外观
White to Off-White Solid
熔点
205-208°C
安全信息
MSDS下载
保存条件
-20°C Freezer
产品相关信息
质检报告
描述信息
A potent and selective agonist of the excitatory neurotransmitter L-glutamic Acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists.
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参考文献
• Honore, T., et al.: J. Neurochem., 38, 173 (1980)
• MacDonald, J.F., et al.: Science, 253, 1132 (1991)
• Krogsgaard-Larsen, et al.: Nature, 284, 64 (1980)