物质信息
ID:372900
名称和标识
IUPAC标准名
(2R)-N-hydroxy-N'-[(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]-2-pentylbutanediamide
IUPAC传统名
actinonin
别名
Ro 06-1467ActinoninCONA 57(2R)-N4-Hydroxy-N1-[(1S)-1-[[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-2-pentyl-butanediamide(-)-Actinonin3-[[1-[[2-(Hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic AcidActinonine
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CAS号
描述信息
(-)-Actinonin is a bioactive peptide and antibiotic that is a potent inhibitor of aminopeptidase M and leucine aminopeptidase. Actinonin has observed to be an inhibitor of peptide deformylase, meprin A, and thermolysin. Actinonin also inhibits tumor cell
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参考文献
• Umezawa, H., et al.: J. Antibiot., 38, 1629 (1985)
• Escobar-Alvarez, S., et al.: J. Mol. Biol., 387, 1211 (1985)
• Berg, A., et al.: Biochem., 48, 1584 (1985)
• Kuehlmann, U., et al.: Life Sci., 84, 1 (1985)