Biochem/physiol Actions The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration. Caution 储存期间由于氧化造成颜色改变,但不会影响大多数应用。只有蒸馏之后才能得到无色产物。