物质信息
ID:360853
名称和标识
IUPAC传统名
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
IUPAC标准名
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
别名
辣椒碱Capsaicin8-甲基-N-香草基-反-6-壬烯酰胺8-Methyl-N-vanillyl-trans-6-nonenamide
化合物性质
安全信息
欧盟危险性物质标志
有毒 (T)RID/ADR
UN 2811 6.1/PG 2
GHS危险声明
H301-H315-H317-H318-H334-H335
GHS危险品标识
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
急性毒性（口服，皮肤接触，吸入），类别1,2,3
GHS警示词
Danger
个人保护装置
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
MSDS下载
GHS警示性声明
P261-P280-P301+P310-P305+P351+P338-P342+P311
危险公开号
25-37/38-41-42/43
RTECS编号
RA8530000
保存温度
2-8°C
联合国危险货物包装类别(PG)
2
安全公开号
22-26-28-36/39-45
联合国危险货物等级
6.1
德国WGK号
3
联合国危险货物编号
2811
理化性质
闪点
235.4 °F
113 °C
熔点
62-65 °C(lit.)
产品相关信息
线性分子式
(CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)
纯度
≥99.0% (HPLC)
描述信息
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
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