物质信息
ID:358923
名称和标识
IUPAC传统名
floxuridine
IUPAC标准名
5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
别名
Floxuridine5-Fluoro-2′-deoxyuridine2′-Deoxy-5-fluorouridineFUDR
化合物性质
安全信息
个人保护装置
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECS编号
YU7525000
联合国危险货物包装类别(PG)
3
GHS警示词
Danger
联合国危险货物等级
6.1
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
德国WGK号
3
GHS警示性声明
P301+P310
危险公开号
22
安全公开号
22-36
联合国危险货物编号
2811
保存温度
2-8°C
GHS危险声明
H301
RID/ADR
UN 2811 6.1/PG 3
欧盟危险性物质标志
有害性 (Xn)MSDS下载
产品相关信息
Empirical Formula (Hill Notation)
C9H11FN2O5
纯度
≥98.0% (HPLC)
理化性质
比旋光度
[α]20/D +38±1°, c = 1% in H2O
熔点
148-150 °C
148 °C(lit.)
描述信息
Biochem/physiol Actions
Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase1 Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.2
Other Notes
Inhibits DNA synthesis by prior inhibition of thymidylate synthetase3
Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase1 Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.2
Other Notes
Inhibits DNA synthesis by prior inhibition of thymidylate synthetase3
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