物质信息
ID:351987
名称和标识
IUPAC传统名
nicotinamide
IUPAC标准名
pyridine-3-carboxamide
别名
Nicotinic acid amidePyridine-3-carboxylic acid amide维生素 B3烟碱酰胺烟酰胺维生素 PPNicotinamide尼克酰胺吡啶-3-甲酰胺niacinamideVitamin PPVitamin B3
化合物性质
产品相关信息
痕量阳离子
Ca: ≤10 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Fe: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Na: ≤50 mg/kg
Cu: ≤5 mg/kg
Zn: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
痕量阴离子
chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg
燃烧残渣
≤0.2%
Empirical Formula (Hill Notation)
C6H6N2O
干燥失重
≤0.2% loss on drying, 20 °C (HV)
纯度
≥99.5% (HPLC)
药理学性质
相关基因信息
human ... PARP1(142), SIRT2(22933)
安全信息
GHS警示性声明
P261-P305+P351+P338
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
欧盟危险性物质标志
刺激性 (Xi)MSDS下载
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
安全公开号
26-36
GHS警示词
Warning
危险公开号
36/37/38
德国WGK号
1
RTECS编号
QS3675000
GHS危险声明
H315-H319-H335
理化性质
闪点
150 °C
302 °F
熔点
128-131 °C
128-131 °C(lit.)
描述信息
Other Notes
Coenzymes and Cofactors, vol. 2: Pyridine Nucleotide Coenzymes1,2
Biochem/physiol Actions
Nicotinamide (Niacinamide) (Nam) is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). Nicotinamide may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule.
Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor
Coenzymes and Cofactors, vol. 2: Pyridine Nucleotide Coenzymes1,2
Biochem/physiol Actions
Nicotinamide (Niacinamide) (Nam) is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). Nicotinamide may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule.
Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor
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