物质信息
ID:351980
名称和标识
IUPAC标准名
(4S,4aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
IUPAC传统名
aureomycin hydrochloride
别名
氯四环素 盐酸盐金霉素 盐酸盐7-Chlorotetracycline hydrochlorideChlortetracycline hydrochloride
化合物性质
产品相关信息
杂质
≤3% water
产品线
BioReagent
适用性
suitable for fluorescence
Empirical Formula (Hill Notation)
C22H23ClN2O8 · HCl
生物来源
from Streptomyces aureofaciens
纯度
≥97.0% (AT)
安全信息
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
危险公开号
36/37/38
GHS警示性声明
P261-P305+P351+P338
MSDS下载
RTECS编号
QI7800000
GHS警示词
Warning
GHS危险声明
H315-H319-H335
欧盟危险性物质标志
刺激性 (Xi)安全公开号
26
德国WGK号
2
保存温度
-20°C
理化性质
熔点
210-215 °C (dec.)(lit.)
荧光
λex 392 nm; λem 536 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+
描述信息
Application
Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Biochem/physiol Actions
Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline.Mode of Resistance: Loss of cell wall permeability.
Quality
Recommended for fluorescent studies of calcium signaling in cells or tissues.
Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Biochem/physiol Actions
Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline.Mode of Resistance: Loss of cell wall permeability.
Quality
Recommended for fluorescent studies of calcium signaling in cells or tissues.
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