物质信息
ID:350784
名称和标识
IUPAC传统名
finasteride
别名
MK-906N-(2-甲基-2-丙基)-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-甲酰胺非那甾胺FinasterideN-tert-Butyl-3-oxo-4-aza-5α-androst-1-en-17β-carboxamideN-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamideN-叔丁基-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-甲酰胺
IUPAC标准名
(1S,2R,7R,10S,11S,14S,15S)-N-tert-butyl-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.02,7.011,15]heptadec-3-ene-14-carboxamide
化合物性质
安全信息
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
RTECS编号
CL5245000
MSDS下载
德国WGK号
3
GHS警示词
Warning
危险公开号
22
个人保护装置
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS危险声明
H302
欧盟危险性物质标志
有害性 (Xn)产品相关信息
纯度
≥98% (HPLC)
Empirical Formula (Hill Notation)
C23H36N2O2
理化性质
外观
white to beige powder
溶解度
DMSO: soluble >20 mg/mL
药理学性质
相关基因信息
human ... HSD3B1(3283), SRD5A1(6715), SRD5A2(6716)rat ... Hsd3b1(360348), Srd5a1(24950), Srd5a2(64677)
描述信息
Biochem/physiol Actions
选择性 5α-还原酶抑制剂；抗雄激素。
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. F1293.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
选择性 5α-还原酶抑制剂；抗雄激素。
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. F1293.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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参考文献
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