物质信息
ID:350012
名称和标识
IUPAC标准名
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
IUPAC传统名
forskolin
别名
Coleonol7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-oneForskolinColforsin
化合物性质
安全信息
GHS警示词
Warning
RTECS编号
QL6150000
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
GHS警示性声明
P280
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS危险声明
H312
德国WGK号
3
欧盟危险性物质标志
有害性 (Xn)MSDS下载
危险公开号
21
安全公开号
22-36/37
产品相关信息
纯度
≥98%
产品线
BioReagent
生物来源
from Coleus forskohlii
级别
for molecular biology
Empirical Formula (Hill Notation)
C22H34O7
药理学性质
相关基因信息
human ... OPRK1(4986), SLC2A10(81031), TNF(7124)
描述信息
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Analysis Note
Tested for inhibition of interleukin-2 production by Jurkat cells.
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
Live Chat and Frequently Asked Questions are available for this Product.
Analysis Note
Tested for inhibition of interleukin-2 production by Jurkat cells.
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
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