物质信息
ID:349953
名称和标识
IUPAC标准名
4-hydroxyquinoline-2-carboxylic acid
IUPAC传统名
kynurenic acid
别名
4-羟基喹啉-2-甲酸4-Hydroxyquinoline-2-carboxylic acidKynurenic acid犬尿喹啉酸
化合物性质
安全信息
欧盟危险性物质标志
刺激性 (Xi)GHS危险声明
H315-H319-H335
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
危险公开号
36/37/38
GHS警示词
Warning
安全公开号
26-36
GHS警示性声明
P261-P305+P351+P338
德国WGK号
3
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
MSDS下载
产品相关信息
Empirical Formula (Hill Notation)
C10H7NO3
纯度
≥98%
药理学性质
相关基因信息
human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143), GRIA3(2892), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIK5(2901), GUCA2A(2980), GUCA2B(2981), NGFR(4804), SLC23A2(9962)rat ... Gria1(50592), Grik1(29559), Grin2a(24409)
理化性质
熔点
275 °C (dec.)(lit.)
描述信息
Biochem/physiol Actions
Kynurenic acid is a non-selective antagonist at NMDA and AMPA/kainate receptors; blocks kainic acid neurotoxicity. Kainic acid also blocks nicotinic acetycholine receptors.
Kynurenic acid is a non-selective antagonist at NMDA and AMPA/kainate receptors; blocks kainic acid neurotoxicity. Kainic acid also blocks nicotinic acetycholine receptors.
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