物质信息
ID:349810
名称和标识
别名
MTTMethylthiazolyldiphenyl-tetrazolium bromide3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromideThiazolyl Blue Tetrazolium Bromide
IUPAC标准名
2-(dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-3H-1,2λ5,3,4-tetrazol-2-ylium bromide
IUPAC传统名
2-(dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-1,2λ5,3,4-tetrazol-2-ylium bromide
化合物性质
安全信息
保存温度
2-8°C
危险公开号
36/37/38-68
GHS警示词
Warning
GHS警示性声明
P261-P281-P305+P351+P338
德国WGK号
3
RTECS编号
XF8060000
MSDS下载
安全公开号
26-36/37
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
欧盟危险性物质标志
有害性 (Xn)GHS危险声明
H315-H319-H335-H341
理化性质
溶解度
H2O: soluble5 mg/mL
熔点
195 °C (dec.)(lit.)
外观
powder
产品相关信息
适用性
suitable for cell culture
suitable for insect cell culture
Empirical Formula (Hill Notation)
C18H16BrN5S
产品线
BioReagent
纯度
≥97.5% (HPLC)
描述信息
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Use as a colorimetric metabolic activity indicator in cell viability assays.
Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation.1,2,3,4,5 MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells. The blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent6 and for the detection of NAD.7 ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used.8 MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.9
包装
1 g in glass bottle
15, 100, 500 mg in glass bottle
Live Chat and Frequently Asked Questions are available for this Product.
Application
Use as a colorimetric metabolic activity indicator in cell viability assays.
Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation.1,2,3,4,5 MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells. The blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent6 and for the detection of NAD.7 ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used.8 MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.9
包装
1 g in glass bottle
15, 100, 500 mg in glass bottle
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