物质信息
ID:349663
名称和标识
IUPAC标准名
3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
IUPAC传统名
glimepride
别名
Glimepiride
化合物性质
理化性质
熔点
212.2-214.5 °C
外观
white solid
溶解度
DMSO: >10 mg/mL
安全信息
MSDS下载
德国WGK号
3
保存温度
room temp
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
产品相关信息
Empirical Formula (Hill Notation)
C24H34N4O5S
纯度
≥98% (HPLC)
药理学性质
相关基因信息
human ... KCNJ1(3758)
描述信息
Application
Glimepiride is currently used to treat type 2 diabetes.
Biochem/physiol Actions
Glimepiride is a potent blocker of cardiac KATP channels activated by pinacidil with an IC50 of 6.8 nM.
Glimepiride is currently used to treat type 2 diabetes.
Biochem/physiol Actions
Glimepiride is a potent blocker of cardiac KATP channels activated by pinacidil with an IC50 of 6.8 nM.
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