物质信息
ID:349558
名称和标识
IUPAC标准名
5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione
IUPAC传统名
rosiglitazone
别名
rosiglitazoneRosiglitazone5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
化合物性质
理化性质
外观
powder
溶解度
DMSO: ≥10 mg/mL
产品相关信息
线性分子式
C18H19N3O3S
纯度
≥98% (HPLC)
≥98% (HPLC)
安全信息
描述信息
Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.
分子图谱
暂无数据
点击上传数据
参考文献
暂无数据
点击上传数据