物质信息
ID:349259
名称和标识
IUPAC标准名
5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid
IUPAC传统名
lipoic acid
别名
(R)-(+)-1,2-Dithiolane-3-pentanoic acid(R)-6,8-二硫辛酸(R)-(+)-α-硫辛酸(R)-(+)-1,2-二硫戊环基-3-戊酸(R)-(+)-α-Lipoic acid(R)-6,8-硫辛酸(R)-6,8-Dithiooctanoic acid(R)-6,8-Thioctic acid
化合物性质
安全信息
理化性质
闪点
>230 °F
>110 °C
熔点
48-52 °C(lit.)
产品相关信息
Empirical Formula (Hill Notation)
C8H14O2S2
纯度
≥98.0% (HPLC)
光学纯度
enantiomeric excess: ≥98.0% (HPLC)
描述信息
Analysis Note
identity confirmed by LC-MS
Biochem/physiol Actions
(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. 1
identity confirmed by LC-MS
Biochem/physiol Actions
(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. 1
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