物质信息
ID:349198
名称和标识
IUPAC传统名
linezolid
IUPAC标准名
N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
别名
U-100766PNU-100766LinezolidN-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide
化合物性质
理化性质
外观
white to off-white powder
溶解度
DMSO: >20 mg/mL
安全信息
GHS警示性声明
P314
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
GHS警示词
Danger
RTECS编号
AC2720000
德国WGK号
3
保存温度
room temp
MSDS下载
GHS危险声明
H372
产品相关信息
Empirical Formula (Hill Notation)
C16H20FN3O4
纯度
≥98% (HPLC)
药理学性质
作用器官
Bone
描述信息
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Linezolid is an oxazolidinone antimicrobial. It binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase.
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Linezolid is an oxazolidinone antimicrobial. It binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase.
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