物质信息
ID:349165
名称和标识
IUPAC标准名
2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate
IUPAC传统名
nitazoxanide
别名
NitazoxanideNTZ; 2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide
化合物性质
安全信息
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS警示性声明
P261-P305+P351+P338
保存温度
2-8°C
欧盟危险性物质标志
有害性 (Xn)GHS危险声明
H302-H315-H319-H335
GHS警示词
Warning
安全公开号
26-36
MSDS下载
危险公开号
22-36/37/38
德国WGK号
3
产品相关信息
纯度
≥98% (HPLC)
Empirical Formula (Hill Notation)
C12H9N3O5S
描述信息
Biochem/physiol Actions
Nitazoxanide is an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR); Antimicrobial recently found to kill both non-replicating and replicating mycobacteria. FDA approved anti-parasitic drug (2002). Recent work (C & EN Sept. 14, 2009, p. 28) highlights that NTZ kills non-replicating and replicating TB bacteria and no apparent resistance is detected.
Nitazoxanide is an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR); Antimicrobial recently found to kill both non-replicating and replicating mycobacteria. FDA approved anti-parasitic drug (2002). Recent work (C & EN Sept. 14, 2009, p. 28) highlights that NTZ kills non-replicating and replicating TB bacteria and no apparent resistance is detected.
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