物质信息
ID:348909
名称和标识
IUPAC传统名
1-cyclopentyl-3-{1H-pyrrolo[2,3-b]pyridin-5-yl}pyrazolo[3,4-d]pyrimidin-4-amine
IUPAC标准名
1-cyclopentyl-3-{1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine
别名
1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-aminePP121
化合物性质
产品相关信息
Empirical Formula (Hill Notation)
C17H17N7
纯度
≥98% (HPLC)
安全信息
GHS警示词
Warning
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
德国WGK号
1
欧盟危险性物质标志
有害性 (Xn)联合国危险货物等级
6.1
联合国危险货物编号
2811
GHS危险声明
H302
MSDS下载
保存温度
2-8°C
RID/ADR
UN 2811 6.1/PG 3
危险公开号
22
联合国危险货物包装类别(PG)
3
理化性质
溶解度
DMSO: >10 mg/mL
外观
off-white powder
描述信息
Biochem/physiol Actions
PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. PP121 is the first inhibitor active on both Tyrosine kinases and the phosphatidylinositol-3-OH kinase (PI(3)K) family. The inhibitor is not effecting other serine-threonine protein kinases.
PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. PP121 is the first inhibitor active on both Tyrosine kinases and the phosphatidylinositol-3-OH kinase (PI(3)K) family. The inhibitor is not effecting other serine-threonine protein kinases.
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