物质信息
ID:348772
名称和标识
别名
Cryptotanshinone(R)-(-)-1,6,6-Trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione
IUPAC标准名
(14R)-6,6,14-trimethyl-12-oxatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15)-tetraene-16,17-dione
IUPAC传统名
(14R)-6,6,14-trimethyl-12-oxatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15)-tetraene-16,17-dione
化合物性质
理化性质
比旋光度
[α]/D -85.0±3.0°, c = 0.1 in chloroform
安全信息
MSDS下载
GHS警示性声明
P273-P301+P310-P501
RTECS编号
SF8282645
欧盟危险性物质标志
有毒 (T)
环境危害性 (N)安全公开号
45-60-61
保存温度
2-8°C
GHS危险品标识
对水环境的危害
急性危害，类别1
慢性危害，类别1,2
急性毒性（口服，皮肤接触，吸入），类别1,2,3
GHS危险声明
H301-H410
GHS警示词
Danger
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
危险公开号
25-50/53
德国WGK号
3
产品相关信息
纯度
≥90% (HPLC)
Empirical Formula (Hill Notation)
C19H20O3
描述信息
Biochem/physiol Actions
Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation1 and to inhibit macrophage migration negatively regulate the PI3K pathway.2,3 It has demonstrated activity against several strains of Staphylococcus aureus.4
Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation1 and to inhibit macrophage migration negatively regulate the PI3K pathway.2,3 It has demonstrated activity against several strains of Staphylococcus aureus.4
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