Mirtazapine

Sigma Aldrich

ID: M0443

名称和标识

IUPAC传统名

mirtazapine

IUPAC标准名

5-methyl-2,5,19-triazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(15),8,10,12,16,18-hexaene

别名

1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepineMirtazapine

数据登录号

MDL号

MFCD00865427

PubChem SID

24724531

CAS号

85650-52-8

化合物性质

产品相关信息

纯度

≥98% (HPLC)

Empirical Formula (Hill Notation)

C17H19N3

药理学性质

相关基因信息

human ... ADRA2A(150), ADRA2C(152), DRD2(1813), DRD3(1814), DRD4(1815), HRH1(3269), HTR1A(3350), HTR2A(3356), HTR2C(3358), HTR7(3363)mouse ... Slc6a2(20538)rat ... Adra1a(29412), Drd1a(24316), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr2c(25187), Slc6a3(24898), Slc6a4(25553)

理化性质

溶解度

DMSO: soluble ~8 mg/mL

外观

white powder

安全信息

个人保护装置

Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

MSDS下载

下载链接

德国WGK号

描述信息

Biochem/physiol Actions
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT1A mediated serotonergic signaling are increased.

分子图谱

暂无数据

点击上传数据

参考文献