物质信息
ID:348254
名称和标识
IUPAC传统名
ifosfamide
别名
IfexN,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxideIfosfamide
IUPAC标准名
3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2λ5-oxazaphosphinan-2-one
化合物性质
安全信息
GHS警示词
Danger
MSDS下载
RTECS编号
RP6050000
联合国危险货物等级
6.1
德国WGK号
3
RID/ADR
UN 2811 6.1/PG 3
危险公开号
25-36
保存温度
2-8°C
GHS警示性声明
P301+P310-P305+P351+P338
联合国危险货物编号
2811
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
欧盟危险性物质标志
有毒 (T)联合国危险货物包装类别(PG)
3
GHS危险声明
H301-H319
个人保护装置
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
安全公开号
26-45
产品相关信息
Empirical Formula (Hill Notation)
C7H15Cl2N2O2P
纯度
≥98%
运输包装
wet ice
描述信息
Biochem/physiol Actions
Ifosfamide is a nitrogen mustard compound that is a structural isomer of cyclophosphamide. Ifosfamide is a prodrug that must be transformed by cytochrome P450 to the biologically active component. It is used as an antineoplastic agent in cancer chemotherapy, but ifosfamide is more likely to cause renal toxicity than cyclophosphamide.
Ifosfamide is a nitrogen mustard compound that is a structural isomer of cyclophosphamide. Ifosfamide is a prodrug that must be transformed by cytochrome P450 to the biologically active component. It is used as an antineoplastic agent in cancer chemotherapy, but ifosfamide is more likely to cause renal toxicity than cyclophosphamide.
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