物质信息
ID:348165
名称和标识
别名
ICI 182,780FaslodexZD 182780ZD 9238ZM 182780(7a,17b)-7-[9-[(4,4,5,5,5pentafluoropentyl)Sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diolFulvestrant
IUPAC标准名
(1S,9R,10R,11S,14S,15S)-15-methyl-9-[9-(4,4,5,5,5-pentafluoropentanesulfinyl)nonyl]tetracyclo[8.7.0.02,7.011,15]heptadeca-2,4,6-triene-5,14-diol
IUPAC传统名
fulvestrant
化合物性质
安全信息
保存温度
2-8°C
MSDS下载
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS编号
KG7623000
德国WGK号
3
产品相关信息
纯度
>98% (HPLC)
Empirical Formula (Hill Notation)
C32H47F5O3S
理化性质
溶解度
DMSO: >5 mg/mL
外观
powder
描述信息
Biochem/physiol Actions
Fulvestrant (ICI 182,780) is a selective estrogen receptor down-regulator (SERD). Fulvestrant is a high affinity estrogen receptor antagonist. IC50 = 0.29 nM. Fulvestrant is the first "pure" antiestrogen with no agonistic activity both in vitro and in vivo.
Fulvestrant (ICI 182,780) is a selective estrogen receptor down-regulator (SERD). Fulvestrant is a high affinity estrogen receptor antagonist. IC50 = 0.29 nM. Fulvestrant is the first "pure" antiestrogen with no agonistic activity both in vitro and in vivo.
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