物质信息
ID:348101
名称和标识
IUPAC标准名
1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
别名
Akineton1-(5-Bicyclo[2.2.1]hept-2-enyl)-1-phenyl-3-(1-piperidinyl)propan-1-ol hydrochlorideBiperiden hydrochlorideAkinophylBiperiden 盐酸盐
IUPAC传统名
biperiden hydrochloride
化合物性质
产品相关信息
Empirical Formula (Hill Notation)
C21H30ClNO
纯度
≥98% (HPLC)
安全信息
德国WGK号
3
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
欧盟危险性物质标志
有害性 (Xn)GHS警示性声明
P305+P351+P338
GHS危险声明
H302-H319
GHS警示词
Warning
RTECS编号
TN3706000
危险公开号
22
MSDS下载
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
理化性质
溶解度
DMSO: >20 mg/mL
H2O: insoluble
外观
off-white powder
描述信息
Biochem/physiol Actions
Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. It is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. LD50 in rats 750 mg/kg; in dogs 340 mg/kg.
Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. It is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. LD50 in rats 750 mg/kg; in dogs 340 mg/kg.
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