物质信息
ID:347705
名称和标识
别名
[R-(E)]-4-Hydroxy-3,5-dimethyl-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenoneThiolactomycinAntibiotic 2-200(5R)-4-Hydroxy-3,5-dimethyl-5-[(1E)-2-methyl-1,3-butadienyl]-2(5H)-thiophenone
IUPAC传统名
(5R)-4-hydroxy-3,5-dimethyl-5-(2-methylbuta-1,3-dien-1-yl)thiophen-2-one
IUPAC标准名
(5R)-4-hydroxy-3,5-dimethyl-5-(2-methylbuta-1,3-dien-1-yl)-2,5-dihydrothiophen-2-one
化合物性质
理化性质
外观
light yellow solid
溶解度
H2O: insoluble
DMSO: soluble ~21 mg/mL
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
德国WGK号
3
MSDS下载
RTECS编号
XN1928870
药理学性质
相关基因信息
human ... FASN(2194)
产品相关信息
Empirical Formula (Hill Notation)
C11H14O2S
纯度
98% (HPLC)
描述信息
Biochem/physiol Actions
Inhibitor of bacterial myristate synthesis. Does not inhibit eukaryotic myristate synthesis; antibiotic; antitrypanosomal. Shown to be effective against human sleeping sickness parasite, Trypanosoma brucei, as well as malaria parasite and toxoplasma.
Inhibitor of bacterial myristate synthesis. Does not inhibit eukaryotic myristate synthesis; antibiotic; antitrypanosomal. Shown to be effective against human sleeping sickness parasite, Trypanosoma brucei, as well as malaria parasite and toxoplasma.
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