物质信息
ID:312312
名称和标识
别名
反式-脱氢雄甾酮普拉睾酮去氢表雄酮脱氢异雄酮雄素-5-烯-3β-醇-17-酮DHEA3β-羟基-5-雄烯-17-酮trans-Dehydroandrosterone5-Androsten-3β-ol-17-onePrasteroneDehydroepiandrosteroneDehydroisoandrosterone3β-Hydroxy-5-androsten-17-one
IUPAC传统名
dehydroepiandrosterone
IUPAC标准名
(1S,2R,5S,10R,11S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-7-en-14-one
化合物性质
产品相关信息
纯度
97%
Empirical Formula (Hill Notation)
C19H28O2
安全信息
GHS危险声明
H315-H319-H335
毒品管制信息
regulated under CDSA - not available from Sigma-Aldrich Canada
GHS警示词
Warning
安全公开号
26-36
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
RTECS编号
BV8396000
MSDS下载
危险公开号
36/37/38
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
德国WGK号
2
欧盟危险性物质标志
刺激性 (Xi)GHS警示性声明
P261-P305+P351+P338
理化性质
熔点
149-151 °C(lit.)
比旋光度
[α]25/D +13.0°, c = 1 in ethanol
描述信息
Biochem/physiol Actions
Negative modulator of GABAA receptors. Steroid secreted by the adrenal gland with both estrogenic and androgenic properties. Its conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. At high but physiologically valid concentrations, DHEA inhibits proliferation of chromaffin progenitor cells and induces dopaminergic differentiation.1
Negative modulator of GABAA receptors. Steroid secreted by the adrenal gland with both estrogenic and androgenic properties. Its conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. At high but physiologically valid concentrations, DHEA inhibits proliferation of chromaffin progenitor cells and induces dopaminergic differentiation.1
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参考文献
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