物质信息
ID:2647
名称和标识
别名
5a-DihydrotestosteroneAndrostan-17b-ol-3-oneDihydrotestosterone17beta-Hydroxy-5alpha-androstane-3-oneAndrostan-17beta-ol-3-one(5a,17b)-17-Hydroxyandrostan-3-one17beta-Hydroxy-5alpha-androstan-3-one17beta-Hydroxyandrostan-3-one(5alpha,17beta)-17-hydroxyandrostan-3-one4-Dihydrotestosterone5alpha-Dihydrotestosterone5.alpha.-DihydrotestosteroneStanolone5alpha dihydrotestosteroneAnaboleenAndroloneAndrostanoloneStanaprol
商标名
AnabolexProtonaAnaprotinCristerona MBNeodrolAndractimProteina
IUPAC传统名
dihydrotestosterone
IUPAC标准名
14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one
化合物性质
理化性质
疏水性(logP)
3.55 [HANSCH,C ET AL. (1995)]
描述信息
Drug Groups
illicit; experimental
Description
A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid. [PubChem]
Toxicity
Oral LD50 in rat is 7060 mg/kg. Oral LD50 in mouse is 3450 mg/kg.
Affected Organisms
Humans and other mammals
Absorption
Bioavailability is very low (0-2%) following oral administration.
External Links
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