物质信息
ID:1867964
名称和标识
别名
conivaptan4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilideConivaptan
国际非专利药品(INN)
conivaptan
IUPAC标准名
N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0²,⁶]tetradeca-1(10),2(6),4,11,13-pentaene-9-carbonyl}phenyl)-[1,1'-biphenyl]-2-carboxamide
IUPAC传统名
N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),2(6),4,11,13-pentaene-9-carbonyl}phenyl)-[1,1'-biphenyl]-2-carboxamide
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化合物性质
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描述信息
The amide resulting from the formal condensation of 4-[(biphenyl-2-ylcarbonyl)amino]benzoic acid with the benzazepine nitrogen of 2-methyl-1,4,5,6-tetrahydroimidazo[4,5-d][1]benzazepine. It is an antagonist for two of the three types of arginine vasopressin (AVP) receptors, V1a and V2. It is used as its hydrochloride salt for the treatment of hyponatraemia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH).
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