物质信息

ID:1855097

名称和标识
IUPAC传统名
panobinostat
IUPAC标准名
(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide
别名
panobinostatLBH 589LBH589
国际非专利药品(INN)
panobinostat
数据登录号
PubChem CID
Reaxys Registry
BKMS React数据库
BRENDA Ligand数据库
CompTox数据库
PDB数据库
SureChEMBL数据库
维基百科标题
Drug Central Database
BindingDB数据库
KEGG DRUG Database
ArrayExpress (Gene Expression Altlas)
CHEBI ID
PubChem SID
化合物性质
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描述信息
A hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma.
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参考文献
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