物质信息
ID:184741
名称和标识
IUPAC标准名
(6E)-6-(bromomethylidene)-3-(naphthalen-1-yl)oxan-2-one
IUPAC传统名
(6E)-6-(bromomethylidene)-3-(naphthalen-1-yl)oxan-2-one
别名
BELE-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-oneBromoenol lactone
化合物性质
产品相关信息
纯度
≥98%
安全信息
GHS警示词
Warning
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
安全公开号
26
德国WGK号
3
欧盟危险性物质标志
刺激性 (Xi)GHS危险声明
H315-H319-H335
GHS警示性声明
P261-P305+P351+P338
保存温度
-20°C
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
危险公开号
36/37/38
理化性质
溶解度
DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
紫外吸收波长
λmax 224 nm
描述信息
Biochem/physiol Actions
Potent, irreversible inhibitor of calcium-independent phospholipase A2 and of magnesium-dependent phosphatidate phosphohydrolase from P388D macrophages (IC50 = 8 μM); enzyme activated irreversible chymotrypsin inhibitor (Ki = 636 nM).
Potent, irreversible inhibitor of calcium-independent phospholipase A2 and of magnesium-dependent phosphatidate phosphohydrolase from P388D macrophages (IC50 = 8 μM); enzyme activated irreversible chymotrypsin inhibitor (Ki = 636 nM).
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参考文献
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