物质信息
ID:184725
名称和标识
IUPAC标准名
6-(2-{4-[(4-fluorophenyl)(phenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-1H,5H-imidazo[1,2-a]pyrimidin-5-one
别名
6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidin-yl]ethyl]-7-methyl-5H-thiazolo-[3,2-a]-pyrimidin-5-oneR59022Diacylglycerol Kinase Inhibitor I
IUPAC传统名
6-(2-{4-[(4-fluorophenyl)(phenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-1H-imidazo[1,2-a]pyrimidin-5-one
化合物性质
理化性质
溶解度
ethanol: soluble
DMSO: soluble
ethyl acetate: soluble
0.1 M HCl: slightly soluble
0.1 M NaOH: slightly soluble
H2O: insoluble
外观
pale yellow solid
安全信息
德国WGK号
3
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度
-20°C
描述信息
Biochem/physiol Actions
Diacylglycerol kinase inhibitor. Inhibits formation of [38P]1-Oleoxyl-2-acetylglyceryl-3-phosphoric acid (OAPA) in red blood cell membranes: IC50 = 3.3 μM.
Diacylglycerol kinase inhibitor. Inhibits formation of [38P]1-Oleoxyl-2-acetylglyceryl-3-phosphoric acid (OAPA) in red blood cell membranes: IC50 = 3.3 μM.
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参考文献
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