物质信息
ID:184580
名称和标识
IUPAC标准名
(7R,9S,11S,13Z)-14-[(2R,4R,6E,8R,9R,10S,11S)-9,11-dihydroxy-12-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,8,10-trimethyldodec-6-en-2-yl]-7,9,11-trimethyl-1,3-dioxa-2-calcacyclotetradec-13-ene-4,12-dione
IUPAC传统名
(7R,9S,11S,13Z)-14-[(2R,4R,6E,8R,9R,10S,11S)-9,11-dihydroxy-12-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,8,10-trimethyldodec-6-en-2-yl]-7,9,11-trimethyl-1,3-dioxa-2-calcacyclotetradec-13-ene-4,12-dione
别名
Ionomycin calcium salt from Streptomyces conglobatus
化合物性质
安全信息
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
安全公开号
36
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
德国WGK号
3
RTECS编号
NO0650000
保存温度
2-8°C
GHS警示词
Warning
保存条件
desiccated
protect from light
GHS危险声明
H302
欧盟危险性物质标志
有害性 (Xn)危险公开号
22
理化性质
溶解度
DMSO: soluble10 mg/mL
ethanol: soluble
外观
white to off-white powder
产品相关信息
纯度
≥98% (HPLC)
产品质量级别
PREMIUM
描述信息
Preparation Note
Store ionomycin in powder form desiccated and protected from light at 2-8 °C. Under these conditions the product is stable for 3 years. Store stock solutions in ethanol or DMSO at -20 °C, protected from light. Under these conditions the stock solutions are stable for several months. For short term use (up to 6 weeks) the stock solutions maybe stored at 2-8 °C protected from light.
Biochem/physiol Actions
Ca2+ ionophore that is more effective than A23187 as a mobile ion carrier for Ca2+; non-fluorescent; used to study Ca2+ transport across biological membranes; induces apoptotic degeneration of embryonic cortical neurons.
Store ionomycin in powder form desiccated and protected from light at 2-8 °C. Under these conditions the product is stable for 3 years. Store stock solutions in ethanol or DMSO at -20 °C, protected from light. Under these conditions the stock solutions are stable for several months. For short term use (up to 6 weeks) the stock solutions maybe stored at 2-8 °C protected from light.
Biochem/physiol Actions
Ca2+ ionophore that is more effective than A23187 as a mobile ion carrier for Ca2+; non-fluorescent; used to study Ca2+ transport across biological membranes; induces apoptotic degeneration of embryonic cortical neurons.
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