物质信息
ID:184444
名称和标识
IUPAC传统名
triphosphate, guanosine; tris(tris buffer)
IUPAC标准名
({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid; tris(2-amino-2-(hydroxymethyl)propane-1,3-diol)
别名
GTPGuanosine 5′-triphosphate tris salt
数据登录号
CAS号
化合物性质
安全信息
安全公开号
22-26-36-45
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
GHS危险声明
H301-H311-H315-H319-H331-H335
欧盟危险性物质标志
有毒 (T)GHS警示性声明
P261-P280-P301+P310-P305+P351+P338-P311
GHS警示词
Danger
个人保护装置
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
危险公开号
23/24/25-36/37/38
保存温度
-20°C
德国WGK号
3
产品相关信息
运输包装
dry ice
纯度
~95% (HPLC)
理化性质
外观
white powder
溶解度
H2O: soluble50 mg/mL
描述信息
Biochem/physiol Actions
GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
Preparation Note
Prepared from Catalog No. G8877.
GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
Preparation Note
Prepared from Catalog No. G8877.
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