物质信息
ID:184036
名称和标识
IUPAC传统名
ritanserin
IUPAC标准名
6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
别名
Ritanserin6-[2-[4-(bis(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
化合物性质
药理学性质
相关基因信息
human ... HTR2A(3356)rat ... Adra1a(29412), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr7(65032)
理化性质
溶解度
2-hydroxypropyl-β-cyclodextrin: insoluble
dilute aqueous base: insoluble
DMSO: >10.1 mg/mL
methanol: >10 mg/mL
H2O: insoluble
外观
white powder
安全信息
GHS警示性声明
P261-P305+P351+P338
德国WGK号
3
GHS危险声明
H315-H319-H335
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
安全公开号
22-26-36
GHS警示词
Warning
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
危险公开号
36/37/38
欧盟危险性物质标志
刺激性 (Xi)描述信息
Biochem/physiol Actions
Potent 5-HT2A serotonin receptor antagonist/inverse agonist that crosses the blood-brain barrier.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R103.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Potent 5-HT2A serotonin receptor antagonist/inverse agonist that crosses the blood-brain barrier.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R103.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
分子图谱
暂无数据
点击上传数据
参考文献
暂无数据
点击上传数据