物质信息
ID:183997
名称和标识
别名
DFMO hydrochloride hydrateEflornithine hydrochloride hydrateDL-α-Difluoromethylornithine hydrochloride hydrate2-(Difluoromethyl)ornithine hydrochloride hydrate
IUPAC传统名
vaniqa hydrate hydrochloride
IUPAC标准名
2,5-diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride
化合物性质
产品相关信息
纯度
≥97% (NMR)
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
德国WGK号
3
药理学性质
相关基因信息
human ... ODC1(4953)
理化性质
外观
white solid
溶解度
H2O: >10 mg/mL
DMSO: >10 mg/mL
描述信息
Biochem/physiol Actions
Difluoromethylornithine (Eflornithine) inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis.
Difluoromethylornithine (Eflornithine) inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis.
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参考文献
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