物质信息
ID:183794
名称和标识
IUPAC标准名
4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide
IUPAC传统名
merian
别名
4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamideSulfaphenazole
化合物性质
安全信息
德国WGK号
2
RTECS编号
DA9520000
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
药理学性质
相关基因信息
human ... CYP2C18(1562), CYP2C19(1557), CYP2C9(1559)
产品相关信息
纯度
≥98%
描述信息
Biochem/physiol Actions
Antibacterial. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Inhibits bradykinin-induced tPA release.
Antibacterial. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Inhibits bradykinin-induced tPA release.
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