物质信息
ID:183638
名称和标识
IUPAC传统名
triamcinolone
IUPAC标准名
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
别名
9α-Fluoro-11β,16α,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneTriamcinoloneFluoxyprednisolone
化合物性质
药理学性质
相关基因信息
human ... PTGS2(5743)
安全信息
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
欧盟危险性物质标志
有害性 (Xn)安全公开号
22-36
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
德国WGK号
3
危险公开号
40
GHS警示性声明
P281
GHS警示词
Warning
GHS危险声明
H351
RTECS编号
TU3850000
理化性质
熔点
262-263 °C(lit.)
描述信息
Biochem/physiol Actions
Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
包装
1, 5 g in glass bottle
50, 250 mg in glass bottle
Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
包装
1, 5 g in glass bottle
50, 250 mg in glass bottle
分子图谱
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参考文献
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