物质信息
ID:183171
名称和标识
IUPAC传统名
5a-pregnane-3,20-dione
IUPAC标准名
(1S,2S,7S,10R,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-5-one
别名
5α-Pregnane-3,20-dione (allo)5α-DihydroprogesteroneAllopregnane-3,20-dione
化合物性质
安全信息
德国WGK号
3
RTECS编号
TU4157150
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
描述信息
Biochem/physiol Actions
A high-level metabolite of progesterone in breast cancer tissue (but not normal breast tissue); promotes cell proliferation and detachment. Receptors appear only on the cell surface of MCF-7 breast cancer cells, not on nuclei where most other steroid receptors are located.1
A high-level metabolite of progesterone in breast cancer tissue (but not normal breast tissue); promotes cell proliferation and detachment. Receptors appear only on the cell surface of MCF-7 breast cancer cells, not on nuclei where most other steroid receptors are located.1
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参考文献
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