物质信息
ID:183150
名称和标识
别名
Misoprostol(±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1 methyl ester
IUPAC传统名
misoprostol
IUPAC标准名
methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate
化合物性质
安全信息
GHS警示性声明
P201-P301+P310-P308+P313
RID/ADR
UN 2810 6.1/PG 3
保存温度
-20°C
联合国危险货物编号
2810
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
GHS危险声明
H301-H360
欧盟危险性物质标志
有毒 (T)安全公开号
53-45
危险公开号
60-61-25
联合国危险货物等级
6.1
GHS警示词
Danger
联合国危险货物包装类别(PG)
3
德国WGK号
3
药理学性质
相关基因信息
human ... PTGIR(5739)
产品相关信息
纯度
≥99% (TLC)
描述信息
Biochem/physiol Actions
Cytoprotective PGE1 analog that prevents NSAID-induced gastric ulceration.
PGE1 analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-activating factor (PAF), treatment of ethanol- and acetaminophen-induced hepatotoxicity and hepatitis, and stimulation of cartilage repair after injury.1
Cytoprotective PGE1 analog that prevents NSAID-induced gastric ulceration.
PGE1 analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-activating factor (PAF), treatment of ethanol- and acetaminophen-induced hepatotoxicity and hepatitis, and stimulation of cartilage repair after injury.1
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