物质信息
ID:182768
名称和标识
IUPAC标准名
3-(2-chloroethyl)-1-(4-methylcyclohexyl)-3-nitrosourea
别名
司莫司汀SemustineMethyl-CCNUN-(2-氯乙基)-N′-(4-甲基环己基)-N-亚硝脲
IUPAC传统名
semustine
化合物性质
安全信息
GHS警示词
Danger
个人保护装置
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
联合国危险货物等级
6.1
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
急性毒性（口服，皮肤接触，吸入），类别1,2,3
联合国危险货物编号
2811
安全公开号
53-22-26-36/37/39-45
联合国危险货物包装类别(PG)
2
GHS危险声明
H300-H311-H315-H319-H331-H335-H350-H360
GHS警示性声明
P201-P261-P264-P280-P301+P310-P305+P351+P338
RTECS编号
YS5000000
欧盟危险性物质标志
有毒 (T)危险公开号
45-46-23/24/25-36/37/38
RID/ADR
UN 2811 6.1/PG 2
德国WGK号
3
描述信息
Application
Commonly used in pharmacological studies involving:
• Nutrient-sensitized screening for drugs that shift the energy metabolism from mitchondrial respiration to glycolysis1
• CEOP regimen with semustine used as induction chemotherapy in patients with lymphoma2
• Investigations into its use for chemotherapy3,4
Commonly used in pharmacological studies involving:
• Nutrient-sensitized screening for drugs that shift the energy metabolism from mitchondrial respiration to glycolysis1
• CEOP regimen with semustine used as induction chemotherapy in patients with lymphoma2
• Investigations into its use for chemotherapy3,4
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