物质信息
ID:182762
名称和标识
IUPAC传统名
tetralithium(1+) ion [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [dioxido(sulfanylidene)-λ5-phosphanyl phosphonato]oxyphosphonate
别名
Guanosine 5′-[γ-thio]triphosphate tetralithium saltGuanosine 5′-O-(3-thiotriphosphate) tetralithium saltGTPγS tetralithium saltGTP-γ-S-Li4
IUPAC标准名
tetralithium(1+) ion [(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl {[dioxido(sulfanylidene)-λ5-phosphanyl phosphonato]oxy}phosphonate
化合物性质
安全信息
GHS警示词
Warning
GHS危险声明
H315-H319-H335
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
安全公开号
26-36
危险公开号
36/37/38
欧盟危险性物质标志
刺激性 (Xi)德国WGK号
3
GHS警示性声明
P261-P305+P351+P338
保存温度
-20°C
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
产品相关信息
纯度
≥75% (HPLC)
运输包装
dry ice
理化性质
外观
off-white powder
溶解度
H2O: ≥75 mg/mL (Solutions are very unstable; prepare immediately prior to use.)
描述信息
Biochem/physiol Actions
GTP-γ-S is a non-hydrolyzable GTP analog, known for its role as a G-protein activator. It has recently been shown to protect proteins from proteolytic degradation, stimulate GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization in vitro.
GTP-γ-S is a non-hydrolyzable GTP analog, known for its role as a G-protein activator. It has recently been shown to protect proteins from proteolytic degradation, stimulate GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization in vitro.
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