物质信息
ID:1826053
名称和标识
IUPAC标准名
(2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide
IUPAC传统名
leuprorelin
别名
leuprolide(D-Leu(6),des-Gly-NH2(10),Pro-ethylamide(9))-gonadotropin-releasing hormoneL-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamideLeuprorelinpGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHC2H5pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt
国际非专利药品(INN)
leuprorelinaleuprorelineleuprorelinum
数据登录号
PubChem CID
CAS号
KEGG ID
Reaxys Registry
CHEMBL
CompTox数据库
MetaboLights数据库
SureChEMBL数据库
DrugBank ID
Drug Central Database
KEGG DRUG Database
CHEBI ID
PubChem SID
化合物性质
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描述信息
An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-leucyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the acetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.
分子图谱
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参考文献
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