物质信息
ID:182483
名称和标识
IUPAC传统名
6-(phenylamino)quinoline-5,8-dione
IUPAC标准名
6-(phenylamino)-5,8-dihydroquinoline-5,8-dione
别名
6-(Phenylamino)-5,8-quinolinedioneLY83583LY-83,5836-Anilinoquinoline-5,8-quinone
化合物性质
理化性质
溶解度
methanol: soluble11 mg/mL
ethanol: soluble8 mg/mL
0.1 M HCl: soluble1 mg/mL
外观
violet solid
安全信息
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS警示词
Warning
保存温度
2-8°C
欧盟危险性物质标志
刺激性 (Xi)GHS警示性声明
P261-P305+P351+P338
GHS危险声明
H315-H319-H335
危险公开号
36/37/38
安全公开号
26-36
德国WGK号
3
产品相关信息
纯度
≥95% (TLC)
描述信息
Biochem/physiol Actions
Blocks cGMP production; inhibits intracellular Ca2+ release; blocks the effects of nitric oxide. Inhibits antigen-induced leukotriene release.
Application
6-Anilinoquinoline-5,8-quinone inhibits soluble guanylate cyclase and cGMP production. 6-Anilinoquinoline-5,8-quinone also blocks the release of intracellular Ca2+ and antigen-induced leukotrienes.
Blocks cGMP production; inhibits intracellular Ca2+ release; blocks the effects of nitric oxide. Inhibits antigen-induced leukotriene release.
Application
6-Anilinoquinoline-5,8-quinone inhibits soluble guanylate cyclase and cGMP production. 6-Anilinoquinoline-5,8-quinone also blocks the release of intracellular Ca2+ and antigen-induced leukotrienes.
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