物质信息
ID:182407
名称和标识
IUPAC标准名
(2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(1H-indol-3-yl)propanamido]-4-methylpentanamide
别名
[D-Trp6]-Luteinizing hormone releasing hormone[D-Trp6]-LH-RH
IUPAC传统名
triptorelin
化合物性质
产品相关信息
纯度
≥97% (HPLC)
安全信息
德国WGK号
3
危险公开号
60
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
个人保护装置
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS警示性声明
P201-P308+P313
保存温度
-20°C
GHS警示词
Danger
GHS危险声明
H360
欧盟危险性物质标志
有毒 (T)安全公开号
53-22-36/37/39-45
药理学性质
相关基因信息
human ... GNRH1(2796)
理化性质
外观
powder
描述信息
Amino Acid Sequence
Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2
Biochem/physiol Actions
Potent LH-RH agonist with enhanced biological activity due to its slower rate of degradation. Like [D-Lys6]-LH-RH, the D-Trp6 analog has been shown to be effective against cancers expressing the LH-RH receptor. However, unlike the D-Lys6 analog, it is generally used in the unconjugated form.
Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2
Biochem/physiol Actions
Potent LH-RH agonist with enhanced biological activity due to its slower rate of degradation. Like [D-Lys6]-LH-RH, the D-Trp6 analog has been shown to be effective against cancers expressing the LH-RH receptor. However, unlike the D-Lys6 analog, it is generally used in the unconjugated form.
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