物质信息

ID:1823340

名称和标识
IUPAC标准名
4-phenylbutanoic acid
IUPAC传统名
4-phenylbutyric acid
别名
4-phenylbutyric acid4-PHENYL-BUTANOIC ACID4-Phenyl-n-butyric acidBenzenebutyric acidPBAgamma-Phenyl-n-butyric acidgamma-phenylbutyric acidomega-Phenylbutanoic acidomega-phenylbutyric acid
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化合物性质
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描述信息
A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
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