物质信息
ID:182265
名称和标识
IUPAC标准名
(1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadecan]-6'-ene-5,5'-dione
IUPAC传统名
spironolactone
别名
4-Pregnen-21-oic acid-17α-ol-3-one-7α-thiol γ-lactone 7-acetate7α-(Acetylthio)-17α-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactoneSpironolactone
化合物性质
安全信息
安全公开号
53-22-36/37/39-45
GHS警示词
Danger
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
德国WGK号
3
个人保护装置
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
欧盟危险性物质标志
有毒 (T)GHS危险声明
H360
GHS警示性声明
P201-P308+P313
危险公开号
60
理化性质
熔点
207-208 °C(lit.)
药理学性质
相关基因信息
human ... HSD17B1(3292), NR3C2(4306)rat ... Ar(24208)
产品相关信息
纯度
97.0-103.0%
描述信息
Biochem/physiol Actions
Spironolactone is a competitive aldosterone receptor antagonist. Used as potassium sparing diuretic.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. S3378.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Spironolactone is a competitive aldosterone receptor antagonist. Used as potassium sparing diuretic.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. S3378.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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