物质信息
ID:182198
名称和标识
IUPAC标准名
5-ethyl-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
别名
EdoxudineEUdR5-Ethyl-2′-deoxyuridine
IUPAC传统名
edoxudine
化合物性质
安全信息
RTECS编号
YU7500000
德国WGK号
3
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
描述信息
Linkage
Homolog of thymidine
Application
5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels.
Homolog of thymidine
Application
5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels.
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