物质信息
ID:182118
名称和标识
IUPAC标准名
N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide
别名
N-AcetylserotoninN-Acetyl-5-hydroxytryptamineNormelatonin
IUPAC传统名
N-acetylserotonin
化合物性质
药理学性质
相关基因信息
human ... MTNR1A(4543), MTNR1B(4544)
理化性质
溶解度
ethanol: soluble50 mg/mL
外观
white powder
熔点
120-122 °C(lit.)
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度
2-8°C
德国WGK号
3
产品相关信息
纯度
≥99% (TLC)
描述信息
包装
1 g in poly bottle
100, 250 mg in poly bottle
Biochem/physiol Actions
Immediate precursor of melatonin. It is formed from serotonin and acetyl-CoA in a reaction catalyzed by serotonin N-acetyl transferase, the rate-limiting enzyme in melatonin biosynthesis. This indoleamine is a weak agonist at melatonin receptors, and has moderate effects on G-protein stimulation and inhibition of cAMP accumulation.
1 g in poly bottle
100, 250 mg in poly bottle
Biochem/physiol Actions
Immediate precursor of melatonin. It is formed from serotonin and acetyl-CoA in a reaction catalyzed by serotonin N-acetyl transferase, the rate-limiting enzyme in melatonin biosynthesis. This indoleamine is a weak agonist at melatonin receptors, and has moderate effects on G-protein stimulation and inhibition of cAMP accumulation.
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