物质信息
ID:182046
名称和标识
IUPAC传统名
(1S,2S,6R,10S,11R,13S,14R,15R)-14-(decanoyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dien-13-yl decanoate
别名
Phorbol 12,13-didecanoatePDDPhorbol 12,13-dicaprinate
IUPAC标准名
(1S,2S,6R,10S,11R,13S,14R,15R)-14-(decanoyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dien-13-yl decanoate
化合物性质
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度
-20°C
德国WGK号
3
RTECS编号
GZ0653000
理化性质
溶解度
methanol: soluble
ethanol: soluble
DMSO: soluble
外观
white solid
描述信息
Biochem/physiol Actions
Strong NO promoter; potent activator of protein kinase C; promotes iNOS expression in cultured hepatocytes.
Caution
Photosensitive
General description
More potent than phorbol myristate acetate as an inflammatory agent, but weaker as a tumor promoting agent
Reconstitution
A stock solution cannot be made in aqueous media; dissolve in a water-miscible organic solvent before dilution to working concentrations in aqueous media.
Strong NO promoter; potent activator of protein kinase C; promotes iNOS expression in cultured hepatocytes.
Caution
Photosensitive
General description
More potent than phorbol myristate acetate as an inflammatory agent, but weaker as a tumor promoting agent
Reconstitution
A stock solution cannot be made in aqueous media; dissolve in a water-miscible organic solvent before dilution to working concentrations in aqueous media.
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