物质信息

ID:181918

名称和标识
IUPAC标准名
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
IUPAC传统名
melatonin
别名
N-乙酰基-5-甲氧基色胺褪黑素Melatonin
数据登录号
CAS号
Beilstein号
PubChem SID
化合物性质
药理学性质
相关基因信息
human ... MTNR1A(4543), MTNR1B(4544), NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
安全信息
RTECS编号
AC5955000
保存温度
-20°C
德国WGK号
2
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
理化性质
溶解度
H2O: soluble0.1 mg/mL
ethanol: soluble8 mg/mL
外观
off-white powder
熔点
116.5-118 °C(lit.)
产品相关信息
纯度
≥98% (TLC)
描述信息
Caution
Solutions are light sensitive and subject to oxidation.
包装
1, 5, 10 g in glass bottle
250 mg in glass bottle
Biochem/physiol Actions
Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M5250.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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参考文献
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