物质信息
ID:181649
名称和标识
IUPAC标准名
2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
别名
Toradol(±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris saltKetorolac tris salt
IUPAC传统名
ketorolac; tris buffer
化合物性质
安全信息
RTECS编号
UY7759900
RID/ADR
UN 2811 6.1/PG 3
联合国危险货物编号
2811
GHS警示性声明
P261-P301+P310-P305+P351+P338
安全公开号
26-45
联合国危险货物等级
6.1
联合国危险货物包装类别(PG)
3
GHS警示词
Danger
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
欧盟危险性物质标志
有毒 (T)个人保护装置
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
危险公开号
25-36/37/38
GHS危险声明
H301-H315-H319-H335
德国WGK号
3
理化性质
外观
crystalline
溶解度
H2O: soluble15 mg/mL (stable at least one month at -20 °C.)
产品相关信息
纯度
≥99%
药理学性质
相关基因信息
human ... PTGS1(5742)
描述信息
Biochem/physiol Actions
Non-steroidal anti-inflammatory agent and cyclooxygenase (COX) inhibitor that is relatively selective for COX-1. Inhibits the induction of nitric oxide synthase by lipopolysaccharide in a murine macrophage cell line. Part of its analgesic effect may be due to the release of opioid peptides.
Caution
Stable at least 2 years if stored at room temperature.
Non-steroidal anti-inflammatory agent and cyclooxygenase (COX) inhibitor that is relatively selective for COX-1. Inhibits the induction of nitric oxide synthase by lipopolysaccharide in a murine macrophage cell line. Part of its analgesic effect may be due to the release of opioid peptides.
Caution
Stable at least 2 years if stored at room temperature.
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