物质信息
ID:181640
名称和标识
别名
1,4,5,6-Tetrahydro-1-methyl-2-(2-[3-methyl-2-thienyl]ethenyl)pyrimidineMorantel citrate salt
IUPAC标准名
1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine; 2-hydroxypropane-1,2,3-tricarboxylic acid
IUPAC传统名
citro; morantel
化合物性质
安全信息
欧盟危险性物质标志
有害性 (Xn)德国WGK号
3
GHS警示性声明
P280
危险公开号
20/21/22
安全公开号
36
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS警示词
Warning
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
GHS危险声明
H302-H312-H332
描述信息
Application
Morantel is a anthelmintic compound used to treat parasitic infections in livestock1. It is also used to study allosteric potentiation of rat neuronal nicotinic acetylcholine receptors (nAChRs)1 and is used to study nematode nicotinic receptors2.
Biochem/physiol Actions
Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase. Morantel increases the macroscopic currents evoked by acetylcholine (ACh) from nAChRs expressed in Xenopus laevis oocytes up to 8 times1.
Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase.
Morantel is a anthelmintic compound used to treat parasitic infections in livestock1. It is also used to study allosteric potentiation of rat neuronal nicotinic acetylcholine receptors (nAChRs)1 and is used to study nematode nicotinic receptors2.
Biochem/physiol Actions
Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase. Morantel increases the macroscopic currents evoked by acetylcholine (ACh) from nAChRs expressed in Xenopus laevis oocytes up to 8 times1.
Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase.
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